“Ulcinok increases Th1 and T-reg which suppress Th2, the cause of inflammation in the peptic lining. It also increases Th1 and Th1 to stimulate the ability of the killer cells to eliminate H.pylori.” Prof. Dr. Pichaet Wiriyachitra Ph.D., F.R.A.C.I.

The Operation BIM research focuses on ways of balancing the immune system using products derived from natural plants extracts.

Here are the causes and symptoms of peptic ulcers and gastro esophageal reflux disease (GERD) and the efficacy of BIM products in treating them.

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A peptic ulcer is a wound in the lining of the stomach or duodenum. The main causes may be any of the following: excessive amount of acid in the stomach, a weak stomach lining that allows stomach acid to cause sores or erosion of the lining, or the existence of the bacterium Helicobacter pylori, which secretes poison causing chronic wounds.

On the other hand, GERD is a digestive disorder that affects the lower esophageal sphincter and squeezes the stomach, causing food to stay in the stomach longer than normal.

It is the result of acidic digestive fluid in the stomach that regurgitates back into the esophagus. This causes inflammation of the lining of the esophagus.

The main symptoms of both peptic ulcers and GERD are flatulence and heartburn. Other possible symptoms of GERD include suffering from a sore throat, a burning sensation in the tongue or feeling like something is stuck in the throat, having difficulty swallowing food, having burning chest pains, sour-tasting belches causing a bitter taste in the mouth, a dry throat, hoarse voice, or a chronic cough or asthma in some cases. GERD may also be caused by genetic factors.

One way to help the body fight both peptic ulcers and GERD is to stimulate the Th1 and T-reg white blood cells, which results in the reduction of inflammation caused by Th2 white blood cells. Moreover, stimulating Th1 and Th17 white blood cells can increase the capability of the killer white blood cells to destroy bacteria H. pylori in the stomach lining, which cause the stomach lining inflammation.

The Operation BIM research team has developed synergistic substances derived from extracts of mangosteen, black sesame, soy, Centellaasiatica and guava to create dietary supplement capsules which have been proven by Biomedical Technology Research Center to effectively stimulate the action of Th1 and Treg. It can also stimulate the efficacy of Th17 many times.

Volunteers who took 4 Ulcinok capsules per day for 15 days showed an increase in their Th1, Th17, T-reg and decreased of Th2

One way to help the body fight both peptic ulcers and GERD is to stimulate the Th1 and T-reg which result in the reduction of inflammation caused by Th2. Moreover, stimulating Th1 and Th17 cells can increase the ability of the killer cells to destroy bacteria H. pylori in the stomach lining. IL-22 from Th17 will also repair the damage of gastrointestinal tissues.

*Scientific study on the effects of Ulcinok capsules done at the Biomedical Technology Research Centre

Mangosteen is a tropical fruit. The fruit, fruit juice, rind, twig, and bark are used as medicine. It is also used for many conditions such as diarrhea, urinary tract infections (UTIs), gonorrhea, thrush, tuberculosis, menstrual disorders, cancer, osteoarthritis, and an intestinal infection called dysentery. It is also used for stimulating the immune system and improving mental, but so far, there isn’t enough scientific evidence to determine whether or not it is effective for any of them.

Centella asiatica, a perennial herb also known as gotu kola, produces fan-shaped, green leaves that are harvested and used for medicinal purposes. Native to China, Japan, India and Indonesia, the herb has a long history of use in these areas. Medical practitioners in the United States and Europe have recently taken an interest in the herb for its possible health benefits.

Sesamin, a phytoestrogen, or plant estrogen, is a lignan that can be found in the hulls of sesame seeds. Sesame seeds are the source of sesame seed oil and sesame lignan. Another lignan that can be obtained from sesame seeds is sesamolin. Sesamin, has been used for centuries, but recently has become very popular due to the many benefits that can be derived from this natural supplement

The health benefits of guava include the treatment of diarrhea, dysentery, constipation, cough, cold, skin care, high blood pressure, weight loss and scurvy. What makes guava special is that protecting the fruit does not require excessive use of chemical pesticides as in the case of grapes, apple, and other so-called “exotic” fruits. It is one of the least chemically treated and sprayed fruits.

Soy protein is a protein that is isolated from soybean. It is made from soybean meal that has been dehulled and defatted. Dehulled and defatted soybeans are processed into three kinds of high protein commercial products : soy flour, concentrates, and isolates. Soy protein isolate has been used since 1959 in foods for its functional properties. Recently, soy protein popularity has increased due to its use in health food products, and many countries allow health claims for foods rich in soy protein.

Ms. Panida Sithburi – Gastritis

I had gastritis. Whenever i fail to have my meal on time, i always succumbed to abdominal distension, nausea and vomiting which often took two to three days to recover. I had to avoid spicy food because it gives me stomachache. Besides gastritis, i also suffer from allergy & asthma. This made me worry a lot because i would have an attack whenever it happened in a dusty place or when walking up or down the stairs or when i have to take long walks. Whenever there was a sudden change in the weather, I easily feel sick. My mother gave me BIM capsules to try, and reminded me to have meals on time. After about two weeks of taking the capsules, my gastritis was gone. I felt a lot better and my asthma didn’t occur again. I became healthier, and is able to run up and down the stairs with ease. I continued to take BIM capsules which is now reduced to one capsule in the morning and one in the evening..

Ms. Thammarat Manonom – Peptic Ulcer

I had peptic ulcer and used to have indigestion after eating. My stomach would feel bloated like it had a lot of gas, which occurs usually after having dinner, I felt like vomiting. I would stand up, sit, walk around and drink water hoping to distract myself from the pain. My knee bone also made cracking sounds when I moved my legs. Later, my mom gave me BIM and I felt better after just a few days. I have been taking BIM capsules for around one and a half months now – one capsule in the morning and one in the evening. And now I can eat normally and my knees do not hurt anymore..

Mr. Sothon Laichuchai – GERD

I used to have GERD and was also allergic to the morning weather having runny nose and sneezing. I had sharp sudden pain in my stomach and chest. At night, I could hear “krob-krab” sound on my fingers, toes and knees especially when I move around the bed. I searched the web and found BIM capsules. After one month of taking the supplement, my allergic reactions, colic, and chest pains were all alleviated. I could no longer hear the disturbing sound and felt fresh when waking up in the morning. I recommended BIM capsules to my mom who had knee problems and my brother who had gout. They both had good results after taking BIM capsules. I am currently taking the product (one green capsule in the morning and one in the evening) for over five months now and it’s really effective..

Ms. Itsaree Chonchai – GERD

I had GERD and with burning pain in the middle of my chest that made it too difficult for me to breathe. I also experienced burning sensations in my throat and in the epigastric region. Due to the nature of my job, I was to sit with a computer all day and my right arm would ache eventually getting to my neck; rashes were visible whenever I wore a metal watch; my hair strands were also falling whenever I washed my hair. And then, I found BIM by accident on Facebook. I started using the product (two green capsules in the morning, 2 in the evening, and later on decreased it to one capsule in the morning and one in the evening) and the GERD symptoms were all alleviated. I had no more arm and neck pains and no more rashes around my wrist! It’s amazing!.

Ms. Sudarat Singaturat – GERD

I didn’t know that I had GERD until I experienced acid reflux and chest pains. It always started with a burning pain around the lower chest area. I had a sore throat once so I went to see a doctor. I was advised that I need to undergo upper gastrointestinal endoscopy when he noticed that my throat was swollen. The doctor prescribed medicines for me which helped relieve my throat but only for a short period of time. I have had this problem since 1993 and up until now, I still feel the same thing after more than 20 years now. Back then, Thai people don’t have a clue about GERD. My friends said they’ve heard of BIM and showed me brochures about the company and researchers which seemed to have an effect on me as I immediately wanted to trust the products. I then decided to take 2 capsules in the morning and 2 at night. I felt that I wouldn’t be able to finish the whole bottle as I already felt the changes. I started it last December and after suffering for 20, no more sore throat and acid reflux anymore. So far, I’ve finished 3 bottles and I still continue taking on a lower dosage..

Amita Khaosara – Ulcer

I had peptic ulcer and worse than that, I also found out that I had intestine disorder. It usually attacked in the middle of the night and I had to get up hoping doing so would relieve the pain. This also happened before waking up in the morning. I was a workaholic and used to skip meals before. After having acute stomach pains, I went to see a doctor and was given medicine even though I hated taking any. One time, my neighbor showed to me a brochure about the BIM research. I got interested in them especially the articles about other types of diseases. They suggested the medicine in the green bottles and I started taking 2 capsules every day before mealtime. I took them for two consecutive weeks and my bowel movement has normalized after that. Now, everything is okay!.

Jampi Siprai – Ulcer

I’ve been suffering from pains from stomach ulcer for over two years now. I used to have stomach ache, acid reflux and the frequent nauseous feeling. Back then, I didn’t eat food that much and I rarely ate on time. I went to see 2-3 doctors and all said the same thing, that I had peptic ulcer. I was given medication, but did not work out and so I was asked to consult a specialist. The specialist advised me to undergo an ultrasound. He found two lacerations in my stomach. A friend recommended BIM to me, so I tried to take 2 capsules in the morning and 2 at night. After 2-3 weeks of regular intake, I felt better even if it was hard for me to change my eating habits..

Teerawat Yoomarueng – GERD

I had GERD for 3 years. The symptoms included difficulty in breathing, severe chest pain and sore throat. My habits like sleeping late at night, smoking cigarettes, drinking alcohol and this habit of sleeping immediately just right after eating worsened the symptoms. And then, I tried to drink 1 sachet of BIM mangosteen juice and noticed positive results. So, I decided to take 1 sachet of mangosteen juice and accompanied it with the intake of 2 BIM capsules before bedtime. I was surprised because the symptoms I was suffering reduced in just a week. After taking BIM, I could already breathe properly and the symptoms were totally gone. At present, I still continue taking BIM capsules and mangosteen juice and I practice a healthy lifestyle now..

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